STAGE IVC RECTAL CANCER AJCC V8
Clinical trials for STAGE IVC RECTAL CANCER AJCC V8 explained in plain language.
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New drug cocktail shows promise for Tough-to-Treat colorectal cancer
Disease control OngoingThis study tests a combination of three drugs (cetuximab, LY3214996, and abemaciclib) in people with advanced colorectal cancer that has spread and no longer responds to standard therapy. The goal is to see if the combination can shrink tumors and improve survival. About 46 adult…
Matched conditions: STAGE IVC RECTAL CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 16, 2026 23:07 UTC
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New combo therapy targets hard-to-treat colorectal cancer
Disease control OngoingThis study tests a new drug, SX-682, alone and with the immunotherapy nivolumab, in people with a specific type of advanced colorectal cancer that has spread or cannot be removed. The cancer must have a RAS mutation and be microsatellite stable (MSS), which often makes it harder …
Matched conditions: STAGE IVC RECTAL CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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Blood tests may unlock secrets of rectal cancer
Knowledge-focused OngoingThis study looks at tiny cancer cells and DNA pieces floating in the blood of people with rectal cancer. Researchers want to see if these blood markers can tell us how the tumor responds to standard treatment. The study includes about 341 people with rectal cancer and healthy vol…
Matched conditions: STAGE IVC RECTAL CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC