New drug shows promise in halting bone sarcoma growth

NCT ID NCT02389244

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 19 times

Summary

This study tests whether the drug regorafenib can stop or slow the growth of bone sarcomas that have spread to other parts of the body. About 163 patients with advanced osteosarcoma, Ewing sarcoma, chondrosarcoma, or chordoma will receive either regorafenib or a placebo. The main goal is to see if more patients remain progression-free after a set time.

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Contacts and locations

Locations

  • CHU Bretonneau

    Tours, 37000, France

  • Centre Antoine Lacassagne

    Nice, 06189, France

  • Centre Eugene Marquis

    Rennes, 35042, France

  • Centre Francois Baclesse

    Caen, 14176, France

  • Centre Georges Francois Leclerc

    Dijon, 21079, France

  • Centre Léon Berard

    Lyon, 69373, France

  • Centre Oscar Lambret

    Lille, 59020, France

  • Gustave Roussy

    Villejuif, 94800, France

  • Hopital Jean Monjoz

    Besançon, 25030, France

  • Hôpital Cochin

    Paris, 75014, France

  • ICM Val d'Aurelle

    Montpellier, 34298, France

  • Institut Bergonie

    Bordeaux, 33076, France

  • Institut Claudius Regaud

    Toulouse, 31052, France

  • Institut Curie

    Paris, France

  • Institut Paoli Calmettes

    Marseille, 13273, France

  • Institut de Cancérologie Lucien Neuwirth (ICLN)

    Saint-Priest-en-Jarez, 42270, France

  • Institut de cancerologie de l'ouest site Rene Gauducheau

    Saint-Herblain, 44805, France

  • Institut de cancerologie de lorraine alexis Vautrin

    Vandœuvre-lès-Nancy, 54519, France

  • La Timone University Hospital

    Marseille, 13385, France

Conditions

Explore the condition pages connected to this study.