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Could your own lung cells heal COPD? a new stem cell trial aims to find out

NCT ID NCT06946953

Recruiting now Disease control Sponsor: Ruijin Hospital Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study tests an experimental therapy called REGEND001 for people with moderate to severe COPD. The treatment uses a patient's own lung stem cells, collected via a bronchial brush, grown in a lab, and then infused back into the lungs. The goal is to see if it can safely improve the lungs' ability to transfer oxygen and ease symptoms. The trial involves 20 participants and follows them for 24 weeks after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a stem cell therapy made from the patient's own lung cells, called REGEND001
What this could lead to
If successful, this could lead to a treatment that repairs lung damage in COPD patients, potentially improving breathing and quality of life beyond current symptom management.
What could go wrong
This is an early-phase trial with only 20 participants, so results may not apply to all COPD patients. The therapy involves invasive procedures and there is a risk of side effects or no benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ruijin Hospital Hainan Branch, Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Qionghai, Hainan, 571437, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200025, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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