New drug shows promise for Hard-to-Treat breast cancers in Real-World setting

NCT ID NCT06210776

Recruiting now Disease control Sponsor: Daiichi Sankyo Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is tracking 800 Chinese patients with advanced HER2-positive or HER2-low breast cancer who are receiving trastuzumab deruxtecan (T-DXd) in real-world clinics. Researchers want to see how long patients stay on treatment and how well it works outside of clinical trials. The goal is to gather practical evidence on effectiveness and safety for these patient groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: trastuzumab deruxtecan (T-DXd)
What this could lead to: If successful, this study could confirm that trastuzumab deruxtecan is effective and safe for a broader group of Chinese breast cancer patients in everyday clinical practice.
What could go wrong: This is an observational study, not a controlled trial, so results may be less definitive. Side effects like lung inflammation or heart problems are possible with this drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm cancer HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED CANCER BREAST CANCER HER2-LOW BREAST CANCER HER2-POSITIVE BREAST CANCER

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

Affiliated Cancer Hospital and Institute of Guangzhou Medical University
WITHDRAWN

Guangzhou, 510060, China
Affiliated Cancer Hospital of Xinjiang Medical University
RECRUITING

Ürümqi, 830011, China
Affiliated Hospital Of Nantong University
RECRUITING

Nantong, 226001, China
Affiliated Zhongshan Hospital of Dalian University
RECRUITING

Dalian, 116001, China
Anhui Provincial Cancer Hospital
WITHDRAWN

Hefei, 230031, China
Beijing GoBroad Hospital
RECRUITING

Beijing, 102206, China
Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center
RECRUITING

Shenzhen, 518116, China
Cancer Hospital of Shantou University Medical College
RECRUITING

Shantou, 515031, China
Changhai Hospital
RECRUITING

Shanghai, 200433, China
China-Japan Friendship Hospital
RECRUITING

Beijing, 100029, China
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, 200000, China
Fujian Cancer Hospital
RECRUITING

Fuzhou, 350000, China
General Hospital of Ningxia Medical University
WITHDRAWN

Yinchuan, 750003, China
Hainan Cancer Hospital
RECRUITING

Haikou, 570311, China
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, 150081, China
Henan Cancer Hospital
RECRUITING

Zengzhou, 450003, China
Henan Provincial People's Hospital
RECRUITING

Zhengzhou, 463599, China
Jiamusi Cancer Hospital
RECRUITING

Jiamusi, 154007, China
Jiangsu Province Hospital
RECRUITING

Nanjing, 210029, China
Jiangxi Cancer Hospital
RECRUITING

Nanchang, 330000, China
Liaoning Cancer Hospital & Institute
RECRUITING

Shenyang, 110000, China
Nanchang Third Hospital
RECRUITING

Nanchang, 330000, China
Nanjing Drum Tower Hospital
RECRUITING

Nanjing, 210008, China
Ningbo No.2 Hospital
WITHDRAWN

Ningbo, 315010, China
Peking University First Hospital
RECRUITING

Beijing, 100034, China
Peking University Shougang Hospital
RECRUITING

Beijing, 100144, China
Peking University Third Hospital
RECRUITING

Beijing, 100191, China
Qingdao Central Hospital
RECRUITING

Qingdao, 266042, China
Shanxi Provincial Cancer Hospital
RECRUITING

Taiyuan, 030000, China
Sichuan Cancer Hospital
RECRUITING

Chengdu, 610041, China
Sichuan Provincial People's Hospital
RECRUITING

Chengdu, 610072, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
RECRUITING

Guangzhou, 510120, China
Tangshan People's Hospital
RECRUITING

Tangshan, 063001, China
The Affiliated Hospital of Xuzhou Medical University
RECRUITING

Xuzhou, 221004, China
The Fifth Affiliated Hospital, Sun Yat-sen University
RECRUITING

Zhuhai, 519000, China
The Fifth Medical Center of the Chinese PLA General Hospital
WITHDRAWN

Beijing, 100039, China
The First Affiliated Hospital of Henan University of Science & Technology
ACTIVE_NOT_RECRUITING

Luoyang, 450052, China
The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi'an, 710061, China
The First Affiliated Hospital of Xinxiang Medical University
RECRUITING

Xinxiang, 453100, China
The First Affiliated Hospital of Zhengzhou University
WITHDRAWN

Zhengzhou, 100142, China
The First Affilital of Xiamen University
RECRUITING

Xiamen, 361003, China
The First People's Hospital of Foshan
RECRUITING

Foshan, 528000, China
The First People's Hospital of Lianyungang
RECRUITING

Lianyungang, 222002, China
The Peoples of Guangxi Zhuang Autonomous Region
RECRUITING

Nanning, 541000, China
The Second Affiliated Hospital Zhejiang University School of Medicine
RECRUITING

Hangzhou, 310009, China
The Second Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi'an, 710004, China
The University of Hong Kong- Shenzhen Hospital
RECRUITING

Shenzhen, 518053, China
Tianjin Cancer Hospital Airport Hospital
RECRUITING

Tianjin, 300308, China
Weifang People's Hospital
RECRUITING

Weifang, 261044, China
Wenzhou Central Hospital
RECRUITING

Wenzhou, 325000, China
Xi'an International Medical Center Hospital
RECRUITING

Xi'an, 710119, China
Yunnan Cancer Hospital
WITHDRAWN

Kunming, 650118, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, 310022, China
Zhongshan City People's Hospital
RECRUITING

Zhongshan, 528403, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.