Can hospitals safely cut unnecessary antibiotics after Kids' surgeries?
NCT ID NCT04366440
First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study compares two strategies to reduce unnecessary antibiotic use after low-risk surgeries in children. One approach involves changing standard order sets to remove automatic post-operative antibiotics. The other adds extra training and support for hospital staff to help them adopt these changes. The goal is to see which method works better at cutting antibiotic use without increasing surgical site infections.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could establish a safe, effective way to reduce unnecessary antibiotic use in children after low-risk surgeries, helping fight antibiotic resistance.
- What could go wrong
- The study focuses on changing hospital practices, not a new drug or treatment. Success depends on whether hospitals adopt and stick with the changes, and results may vary across different settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Baylor College of Medicine / Texas Children's Hospital
Houston, Texas, 77030, United States
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Harvard Medical School / Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Johns Hopkins University School of Medicine / Johns Hopkins All Children's Hospital
St. Petersburg, Florida, 33701, United States
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The Ohio State University College of Medicine / Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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University of Michigan / CS Mott Children's Hospital
Ann Arbor, Michigan, 48109, United States
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University of Missouri - Kansas City / The Children's Mercy Hospital
Kansas City, Missouri, 64108, United States
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University of Utah / Primary Children's Hospital
Salt Lake City, Utah, 84108, United States
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University of Washington / Seattle Children's Hospital
Seattle, Washington, 98105, United States
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Vanderbilt University / Monroe Carell Jr. Children's Hospital at Vanderbilt
Nashville, Tennessee, 37232, United States
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Washington University in St. Louis / St. Louis Children's Hospital
St Louis, Missouri, 63110, United States
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