Hidden fat in slim women: could exercise and diet cut breast cancer risk?

NCT ID NCT04267796

Ongoing Prevention Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This study tests whether a lifestyle program combining aerobic exercise, strength training, and dietary coaching can reduce breast cancer risk in normal-weight postmenopausal women. The goal is to lower body fat and inflammation, which are linked to higher cancer risk even in women with a healthy BMI. The trial will enroll 40 women to see if the program is feasible and if participants stick with it.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lifestyle intervention (aerobic exercise, resistance training, and dietary recommendations)
What this could lead to: If successful, this could show that a simple diet and exercise program helps lower breast cancer risk in normal-weight women with hidden excess body fat.
What could go wrong: This is a small, early feasibility study with only 40 participants, so results may not apply widely. It focuses on adherence and eligibility, not directly on cancer reduction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast carcinoma breast neoplasm breast cancer prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CARCINOMA

Contacts and locations

Locations

M D Anderson Cancer Center

Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.