Brazilian ICUs test simple training to cut antibiotic overuse

NCT ID NCT07093450

Recruiting now Knowledge-focused Sponsor: Hospital Sirio-Libanes Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether an educational program can help doctors in intensive care units (ICUs) use fewer antibiotics. The program includes training sessions and feedback based on the latest guidelines. Researchers will compare antibiotic use in ICUs before and after the program, involving about 9,000 patients across multiple Brazilian ICUs. They will also check if reducing antibiotics affects patient safety, such as death rates or length of stay.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Educational quality improvement intervention
What this could lead to: If successful, this could show that training and feedback help ICUs use antibiotics more wisely, reducing resistance and side effects without harming patients.
What could go wrong: This is an implementation study, not a drug trial. Results depend on how well doctors follow the program, and it may not work in other settings or countries.

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Conditions

The condition(s) this trial relates to.

Infections infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTIMICROBIAL STEWARDSHIP CRITICALLY ILL INTENSIVE CARE UNIT PATIENTS INFECTION

Contacts and locations

Locations

Hospital Maternidade São José
RECRUITING

Colatina, Espírito Santo, Brazil
Hospital Municipal de Maringá
RECRUITING

Maringá, Paraná, Brazil
Hospital Naval Marcílio Dias
RECRUITING

Rio de Janeiro, Rio de Janeiro, Brazil
Hospital Onofre Lopes
RECRUITING

Natal, Rio Grande do Norte, Brazil
Hospital Pelópidas Silveira
RECRUITING

Recife, Pernambuco, Brazil
Hospital Santa Cruz
RECRUITING

Santa Cruz do Sul, Rio Grande do Sul, Brazil
Hospital de Pronto Socorro
RECRUITING

Porto Alegre, Rio Grande do Sul, Brazil
Santa Casa de Misericórdia de Barretos
RECRUITING

Barretos, São Paulo, Brazil
Santa Casa de Misericórdia de Passos
RECRUITING

Passos, Minas Gerais, Brazil

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