Gentler transplant approach aims to beat blood cancers with fewer side effects
NCT ID NCT05417971
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests a reduced-intensity stem cell transplant for people with blood cancers like leukemia or lymphoma. The approach uses lower doses of chemotherapy and radiation before a half-matched donor transplant. Researchers hope this gentler method will help the body accept the new cells while lowering the chance of the cancer coming back. The study is currently recruiting 20 participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fludarabine and total body irradiation followed by stem cell transplant
What this could lead to
If successful, this could offer a safer transplant option for people with blood cancers, reducing the risk of graft rejection and relapse.
What could go wrong
This is a small, early-phase trial with only 20 participants. The reduced-intensity approach may still carry risks like infection, graft failure, or relapse.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Phone: •••-•••-•••• Email: •••••@•••••
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Locations
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Caitlin Guzowski
RECRUITINGAtlanta, Georgia, 30342, United States
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