Simple surgical tweak may cut prolapse return rate
NCT ID NCT04880239
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding a posterior repair (tightening the vaginal opening) to standard prolapse surgery helps prevent the prolapse from returning within a year. About 200 women with advanced prolapse are taking part. Half get the extra procedure, half do not, and researchers compare recurrence rates.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Posterior colpoperineorrhaphy (a surgical procedure to tighten the vaginal opening)
What this could lead to
If successful, this could show that adding a simple vaginal tightening step during prolapse surgery lowers the chance of prolapse coming back within a year.
What could go wrong
This is a relatively small, single-center trial, so results may not apply to all women. The added procedure could also increase pain or bowel issues without preventing recurrence.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Northwestern University
Chicago, Illinois, 60611, United States