Can a Hormone-Radiation combo save erectile function in prostate cancer?
NCT ID NCT07302451
First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times
Summary
This phase 2 trial is testing whether combining a 12-month course of the hormone therapy Relugolix with precise, image-guided radiation can help men with intermediate-risk prostate cancer recover erectile function. Fifty men will receive the treatment and complete questionnaires about sexual function, quality of life, and financial impact. The main goal is to see if at least 70% of participants regain meaningful erectile function within six months of stopping hormone therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Relugolix (hormone therapy) and stereotactic body radiotherapy (SBRT)
- What this could lead to
- If successful, this approach could help men with intermediate-risk prostate cancer recover erectile function and maintain quality of life after treatment.
- What could go wrong
- This is a small, early-phase study with only 50 participants, so results may not apply to all patients. The hormone therapy can cause side effects like hot flashes and fatigue, and erectile recovery is not guaranteed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Istituto Nazionale Tumori - IRCCS - Fondazione G. Pascale - Napoli
RECRUITINGNaples, 80131, Italy
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