Simple wash during surgery may stop rectal cancer return
NCT ID NCT07512232
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether rinsing the rectal cavity with a saltwater or iodine solution during laparoscopic surgery can prevent local recurrence of mid-to-low rectal cancer. About 1,600 patients will be randomly assigned to receive the wash or not, and they will be followed for five years. The goal is to see if this simple step reduces the chance of cancer growing back near the surgery site.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
rectal irrigation with normal saline or povidone-iodine
What this could lead to
If it works, this simple procedure could become a standard step during rectal cancer surgery to lower the chance of cancer returning.
What could go wrong
This is a large trial, but the procedure is new for this purpose and may not reduce recurrence. There is also a small risk of infection or irritation from the wash.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, 518000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••