Boosting radiation may help more rectal cancer patients reach remission

NCT ID NCT07200141

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a higher dose of radiation (58.75 Gy) given before surgery can help more people with locally advanced rectal cancer achieve a complete response (no cancer left) compared to the standard dose (50 Gy). About 156 adults aged 18-79 will receive radiation plus chemotherapy, then either surgery or a watch-and-wait approach. The goal is to improve tumor control and possibly avoid surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.