Higher radiation dose may boost rectal cancer remission

NCT ID NCT07200141

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 28 times

Summary

This phase 2 trial tests whether a higher radiation dose (58.75 Gy) given before surgery can improve complete response rates in 156 adults with locally advanced rectal cancer, compared to the standard dose (50 Gy). Participants receive radiation plus chemotherapy, then surgery or watchful waiting. The study aims to see if the stronger dose leads to better tumor shrinkage and long-term control.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED RECTAL ADENOCARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

Explore the condition pages connected to this study.