New tetracycline drugs take on superbugs in Real-World trial

NCT ID NCT06990126

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This real-world study is testing two neotetracycline drugs, eravacycline and tigecycline, in 300 adults with drug-resistant Gram-negative bacterial infections. Researchers will track how well the drugs clear the infection and monitor for side effects. The goal is to see if these antibiotics work effectively outside of strict clinical trial conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

neotetracycline drugs (eravacycline and tigecycline)

What this could lead to

If successful, this study could confirm that neotetracycline drugs are effective and safe for treating hard-to-treat Gram-negative bacterial infections in real-world settings.

What could go wrong

This is an observational, real-world study, not a controlled trial, so results may be less definitive. The study is also relatively small and may not apply to all patient groups.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Drug-Related Side Effects and Adverse Reactions gram-negative bacterial infections

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, China