10,000 patients enrolled in global study to find best heart disease treatment
NCT ID NCT01341327
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is observing 10,000 people with severe narrowing in the left main coronary artery, a critical heart vessel. Researchers are comparing the long-term results of three approaches: medication, stenting with drug-coated stents, and bypass surgery. The goal is to see which works best in everyday medical practice, not just in controlled trials.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors choose the best treatment for left main coronary artery disease based on real-world evidence.
- What could go wrong
- This is an observational study, not a controlled trial, so results may be influenced by factors like patient choice or doctor preference. It does not test a new treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ajou University Hospital
TERMINATEDSuwon, South Korea
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Asan Medical Center
RECRUITINGSeoul, 138-736, South Korea
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Bundang CHA Hospital
TERMINATEDSeongnam, South Korea
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Chonbuk National University Hospital
RECRUITINGJeonju, South Korea
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Chonnam National University Hospital
RECRUITINGGwangju, South Korea
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Chungnam National University Hospital
RECRUITINGDaejeon, South Korea
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Daegu Catholic University Medical Center
RECRUITINGDaegu, South Korea
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Dongguk University Medical Center
RECRUITINGSeoul, South Korea
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Gangnam Severance Hospital
RECRUITINGSeoul, South Korea
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Gangneung Asan Medical Center
RECRUITINGGangneung, South Korea
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Hallym University medical center
RECRUITINGAnyang, South Korea
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Inje University Busan Paik Hospital
RECRUITINGBusan, South Korea
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Kangbuk samsung hospital
RECRUITINGSeoul, South Korea
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Kangdong Sacred Heart Hospital
RECRUITINGSeoul, South Korea
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Keimyung University Dongsan Medical Center
RECRUITINGDaegu, South Korea
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Korea University Anam hospital
RECRUITINGSeoul, South Korea
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Korea University Guro Hospital
RECRUITINGSeoul, South Korea
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Kwangju Christian hospital
RECRUITINGKwangju, South Korea
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National Health Insurance Service Ilsan Hospital
TERMINATEDIlsan, South Korea
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Presbyterian Medical Center
RECRUITINGJeonju, South Korea
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Pusan Natioanal University Hospital
RECRUITINGPusan, South Korea
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Sarawak General Hospital
RECRUITINGKuching, Malaysia
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Seoul National University Boramae Medical Center
RECRUITINGSeoul, South Korea
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Seoul National University Hospital
RECRUITINGSeoul, South Korea
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Seoul Veterans Hospital
TERMINATEDSeoul, South Korea
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Shin Kong Hospital
RECRUITINGTaipei, Taiwan
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Siriraj Hospital
RECRUITINGBangkok, Thailand
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Soonchunhyang University Hospital, Buchen
TERMINATEDBucheon-si, South Korea
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Soonchunhyang University Hospital, Cheonan
RECRUITINGCheonan, South Korea
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St.Mary's Catholic Medical Center
TERMINATEDCheongju-si, South Korea
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St.Mary's Catholic Medical Center
TERMINATEDInchon, South Korea
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St.Mary's Catholic Medical Center
TERMINATEDSeoul, South Korea
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The Catholic University of Korea, Bucheon ST.Mary's Hospital
TERMINATEDBucheon-si, South Korea
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The Catholic University of Korea, Daejeon ST.Mary's Hospital
TERMINATEDDaejeon, South Korea
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The Catholic University of Korea, ST. Paul's Hospital
TERMINATEDSeoul, South Korea
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The Catholic University of Korea, ST. Vincent's Hospital
RECRUITINGSuwon, South Korea
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The Catholic University of Korea, Yeouido ST. Mary's Hospital
TERMINATEDSeoul, South Korea
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Ulsan University Hospital
RECRUITINGUlsan, South Korea
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Wonju Christian Hospital
RECRUITINGWŏnju, South Korea
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Yeungnam University Medical Center
TERMINATEDDaegu, South Korea
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Yonsei University Medical Center
TERMINATEDSeoul, South Korea
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Zhongshan Hospital
RECRUITINGShanghai, China
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Other studies related to the condition(s) this trial covers.
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- Sitting less could be a lifeline for frail hearts – a new trial tests a simple program
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