Massive Real-World study to see if targeted pills boost survival after lung cancer surgery

NCT ID NCT07593248

Recruiting now Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 5 times

Summary

This observational study will follow about 2,000 patients in China who have early-stage lung cancer with a specific gene mutation (EGFR) and have received targeted therapy pills (EGFR-TKIs) after surgery. Researchers will track how long patients live and how long they stay cancer-free over five years. The goal is to see how well these drugs work in everyday medical practice, outside of controlled clinical trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: EGFR-TKI (a type of targeted therapy pill)
What this could lead to: If successful, this study could provide real-world evidence on how well EGFR-TKIs work as an add-on treatment after surgery for early-stage lung cancer, potentially guiding future treatment decisions.
What could go wrong: This is an observational study, not a controlled trial, so results may be influenced by patient differences and cannot prove cause and effect. It only includes patients in China, so findings may not apply globally.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER

Contacts and locations

Locations

Research Site
NOT_YET_RECRUITING

Beijing, China
Research Site
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Chengdu, China
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Fuzhou, China
Research Site
RECRUITING

Guangzhou, China
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NOT_YET_RECRUITING

Guangzhou, China
Research Site
NOT_YET_RECRUITING

Nanchang, China
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NOT_YET_RECRUITING

Shanghai, China
Research Site
NOT_YET_RECRUITING

Shenyang, China
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NOT_YET_RECRUITING

Shijiazhuang, China
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NOT_YET_RECRUITING

Tianjin, China
Research Site
NOT_YET_RECRUITING

Wuhan, China
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NOT_YET_RECRUITING

Xi'an, China
Research Site
NOT_YET_RECRUITING

Xuzhou, China
Research Site
NOT_YET_RECRUITING

Zhengzhou, China

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