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New study questions need for hormone therapy in older breast cancer patients

NCT ID NCT04921137

Recruiting now Knowledge-focused Sponsor: Ottawa Hospital Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether women aged 70 and older with low-risk breast cancer can safely skip hormone therapy after surgery. Current guidelines recommend at least 5 years of hormone therapy, but older patients may face more side effects with less benefit. The trial will compare outcomes like survival, cancer return, and quality of life between those who take hormone therapy and those who do not.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Allan Blair Cancer Centre

    ACTIVE_NOT_RECRUITING

    Regina, Saskatchewan, S4T 7T1, Canada

  • Cross Cancer Institute

    NOT_YET_RECRUITING

    Edmonton, Alberta, T6G 1Z2, Canada

  • London Health Sciences Centre

    ACTIVE_NOT_RECRUITING

    London, Ontario, N6C 2R5, Canada

  • Oak Valley Health

    ACTIVE_NOT_RECRUITING

    Markham, Ontario, L3P 7P3, Canada

  • Saskatoon Cancer Centre

    ACTIVE_NOT_RECRUITING

    Saskatoon, Saskatchewan, S7N 4H4, Canada

  • The Ottawa Hospital

    RECRUITING

    Ottawa, Ontario, K1H8L6, Canada

  • Thunder Bay Regional Health Sciences Centre

    ACTIVE_NOT_RECRUITING

    Thunder Bay, Ontario, P7B 6V4, Canada

  • Waterloo Regional Health Network

    ACTIVE_NOT_RECRUITING

    Kitchener, Ontario, N2G 1G3, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.