Can engineered immune cells tame lupus? new trial hopes so.

NCT ID NCT06465147

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new treatment for children and young adults (ages 2-30) with severe lupus that hasn't responded to standard therapies. The treatment involves collecting a patient's own immune cells, engineering them to target and destroy faulty B cells (which drive lupus), and infusing them back. The main goals are to check safety and see if the cell product can be made successfully.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

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Other studies related to the condition(s) this trial covers.