Can engineered immune cells tame lupus? new trial hopes so.

NCT ID NCT06465147

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new treatment for children and young adults (ages 2-30) with severe lupus that hasn't responded to standard therapies. The treatment involves collecting a patient's own immune cells, engineering them to target and destroy faulty B cells (which drive lupus), and infusing them back. The main goals are to check safety and see if the cell product can be made successfully.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact