New hope for advanced colon cancer: experimental drug combo enters major trial

NCT ID NCT07462143

First seen Mar 11, 2026 · Last updated May 12, 2026 · Updated 8 times

Summary

This study tests whether a new drug called RC148, combined with chemotherapy, works better than the standard treatment (bevacizumab plus chemo) for people with advanced colorectal cancer that cannot be removed by surgery or has spread. About 700 adults aged 18-75 will take part. The goal is to see if the new combination shrinks tumors more effectively and safely.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of Jiangnan University

    Wuxi, Jiangsu, China

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, China

  • Beijing Friendship Hospital, Capital Medical University

    Beijing, Beijing Municipality, China

  • Chongqing Cancer Hospital

    Chongqing, Chongqing Municipality, China

  • Fujian Medical University Union Hospital

    Fuzhou, Fujian, China

  • Guangxi Medical University Cancer Hospital

    Nanjing, Guangxi, China

  • Jiangsu Cancer Hospital

    Nanjing, Jiangsu, China

  • Meizhou People's Hospital

    Meizhou, Guangdong, China

  • People's Hospital of Tianjin

    Tianjin, Tianjin Municipality, China

  • Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, China

  • Shanxi Cancer Hospital

    Taiyuan, Shanxi, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, China

  • The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital

    Shijiazhuang, Hebei, China

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

  • The first hospital of Jilin University

    Changchun, Jilin, China

  • Tongji Medical College of Huazhong University of Science &Technology

    Wuhan, Hubei, China

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, Hubei, China

  • West China Hospital of Sichuan University

    Chengdu, Sichuan, China

  • Yunnan Cancer Hospital

    Kunming, Yunnan, China

Conditions

Explore the condition pages connected to this study.