New drug aims to unleash immune system on Hard-to-Treat tumors
NCT ID NCT05270213
First seen Jan 09, 2026 · Last updated May 14, 2026 · Updated 20 times
Summary
This early-phase study tests an experimental drug called RBS2418, which works by helping the body's immune system fight cancer more effectively. It is given alone or with another immunotherapy (pembrolizumab) to adults with advanced solid tumors that have not responded to standard treatments. The goal is to find safe doses and see if the drug can shrink tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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American Oncology Partners of Maryland
RECRUITINGBethesda, Maryland, 20817, United States
Contact Email: •••••@•••••
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Carolina BioOncology Institute
COMPLETEDHuntersville, North Carolina, 28078, United States
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Christiana Care Health Services
RECRUITINGNewark, Delaware, 19713, United States
Contact Email: •••••@•••••
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Honor Health Research Institute
RECRUITINGScottsdale, Arizona, 85258, United States
Contact Email: •••••@•••••
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Ichan School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
Contact Email: •••••@•••••
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Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
RECRUITINGBaltimore, Maryland, 21224, United States
Contact Email: •••••@•••••
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NEXT Virigina
RECRUITINGFairfax, Virginia, 22031, United States
Contact Email: •••••@•••••
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Norton Cancer Institute
RECRUITINGLouisville, Kentucky, 40202, United States
Contact Email: •••••@•••••
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Ochsner Clinic Foundation
RECRUITINGNew Orleans, Louisiana, 70121, United States
Contact Email: •••••@•••••
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Stanford Cancer Institute
RECRUITINGPalo Alto, California, 94305, United States
Contact Email: •••••@•••••
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Tranquil Research
WITHDRAWNWebster, Texas, 77598, United States
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UCLA Hematology/Oncology - Santa Monica
RECRUITINGSanta Monica, California, 90404, United States
Contact Email: •••••@•••••
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University of Arizona
RECRUITINGTucson, Arizona, 85724, United States
Contact Email: •••••@•••••
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Vanderbilt-Ingram Cancer Center
RECRUITINGNashville, Tennessee, 37235, United States
Contact Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.