Could a single dose of radiation replace breast cancer surgery?

NCT ID NCT06444269

First seen Nov 05, 2025 · Last updated Apr 24, 2026 · Updated 20 times

Summary

This study tests whether a single, strong dose of radiation given before surgery can eliminate early-stage ER+ breast cancer tumors. About 53 women will receive the radiation, and if the tumor disappears on scans and biopsy, they may avoid surgery. The study also explores using a special ultrasound with microbubbles to check lymph nodes without a surgical biopsy. The goal is to see if this less invasive approach is safe and effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UT Southwestern Medical Center-Dallas

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.