Radioactive water scan could spot hidden heart disease
NCT ID NCT05134012
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial is testing whether a special PET scan using radioactive water ([15-O]-H2O) can accurately detect coronary artery disease. About 215 adults with suspected heart disease will receive the injection at rest and during stress, then compare results to standard tests. The goal is to confirm if this imaging method is a reliable, non-invasive diagnostic tool.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
[15-O]-H2O (radioactive water) injection
What this could lead to
If successful, this could provide a more accurate, non-invasive way to diagnose coronary artery disease, potentially reducing the need for invasive procedures.
What could go wrong
This is a diagnostic trial, not a treatment. The test may not prove accurate enough in all patient groups, and results may not change patient outcomes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Aarhus University Hospital
RECRUITINGAarhus, Denmark
Contact
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Amsterdam University Medical Center, Department of Radiology and Nuclear Medicine
RECRUITINGAmsterdam, North Holland, 1081HV, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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BAMF Healthcare
WITHDRAWNGrand Rapids, Michigan, 49503, United States
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Department of Cardiology and Angiology -- Hannover Medical School (MHH)
RECRUITINGHanover, Germany
Contact
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact
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Norrland University Hospital Heart Center
RECRUITINGUmeå, Sweden
Contact
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Sahlgrenska University Hospital
RECRUITINGGothenburg, Sweden
Contact
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
Contact
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University Hospital Freiburg, Clinic for Nuclear Medicine
RECRUITINGFreiburg im Breisgau, Germany
Contact
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University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States
Contact
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University of Ottawa Heart Institute
RECRUITINGOttawa, Ontario, Canada
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University of Pittsburgh Medical Center
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact
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University of Virginia Medical Center
RECRUITINGCharlottesville, Virginia, 22903, United States
Contact
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
Contact