Rapid heart pump upgrade may save lives in shock

NCT ID NCT07655479

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether quickly upgrading from a standard heart pump (Impella CP) to a more powerful one (Impella 5.5) within 24 hours after a heart attack improves outcomes for people in cardiogenic shock. The trial will enroll 115 adults aged 18-77 who have had a heart attack and need extra heart support. The goal is to see if this faster escalation reduces the need for strong medications and leads to fewer complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Impella heart pumps (Impella CP and Impella 5.5)

What this could lead to

If successful, this could lead to a faster, more effective way to support the heart during cardiogenic shock, potentially reducing complications and improving survival.

What could go wrong

This is a relatively small, early-stage trial (115 people) and the results may not apply to all patients. The procedure itself carries risks like bleeding or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myocardial infarction myocardial infarction Shock, Cardiogenic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital Cologne

    RECRUITING

    Cologne, 50937, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••