Heart rate drug may speed recovery from shock after heart attack

NCT ID NCT07714746

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial tests whether ivabradine, a drug that lowers heart rate, can help people recover from cardiogenic shock—a life-threatening condition where the heart can't pump enough blood—after a heart attack. Participants receive either ivabradine or a placebo for three days, and doctors track their recovery using a scoring system that measures blood pressure, oxygen levels, urine output, and other signs. The goal is to see if ivabradine leads to faster improvement and less need for strong heart-supporting medications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ivabradine, a drug that lowers heart rate
What this could lead to
If it works, ivabradine could offer a new way to help people recover from cardiogenic shock after a heart attack, potentially reducing the need for strong heart-support medications.
What could go wrong
This is a relatively small, early-phase trial, so results may not apply to all patients. Ivabradine can cause side effects like slow heart rate, irregular heartbeat, or low blood pressure.

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Conditions

The condition(s) this trial relates to.

cardiogenic shock Shock, Cardiogenic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National institute of cardiovascular diseases

    RECRUITING

    Karachi, Pakistan

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