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Gene-Guided cancer care: new trials aim to stop endometrial cancer return

NCT ID NCT05255653

Recruiting now Disease control Sponsor: Leiden University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests new treatments for endometrial cancer based on the genetic makeup of each person's tumor. About 1,615 participants will be assigned to one of four trials depending on their cancer's molecular profile. The goal is to see if these tailored therapies can prevent the cancer from coming back.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial carcinoma endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER

Contacts and locations

Locations

  • Amphia Ziekenhuis

    RECRUITING

    Breda, Netherlands

  • Amsterdam University Medical Center

    RECRUITING

    Amsterdam, Netherlands

  • Catharina Ziekenhuis

    RECRUITING

    Eindhoven, Netherlands

  • Erasmus Medical Center

    RECRUITING

    Rotterdam, Netherlands

  • Haags Medisch Centrum

    RECRUITING

    The Hague, Netherlands

  • Instituut Verbeeten

    RECRUITING

    Breda, Netherlands

  • Medisch Spectrum Twente

    RECRUITING

    Enschede, Netherlands

  • The MMRd-GREEN trial: Leiden University Medical Center

    RECRUITING

    Leiden, 2333ZA, Netherlands

  • The NSMP-ORANGE trial: Barts Health NHS Trust

    NOT_YET_RECRUITING

    London, United Kingdom

  • The NSMP-ORANGE trial: Manchester Academic Health Science Centre, St Mary's Hospita

    NOT_YET_RECRUITING

    Manchester, United Kingdom

  • The POLEmut-BLUE trial: Princess Margaret Cancer Centre, University of Toronto

    RECRUITING

    Toronto, Canada

  • The POLEmut-BLUE trial: University of British Columbia

    RECRUITING

    Vancouver, Canada

  • The p53abn-RED trial: Institute Gustave Roussy

    NOT_YET_RECRUITING

    Villejuif, France

  • Universitair Medisch Centrum Groningen

    RECRUITING

    Groningen, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.