Gene-Guided cancer care: new trials aim to stop endometrial cancer return

NCT ID NCT05255653

First seen May 20, 2026 · Last updated Jun 13, 2026 · Updated 5 times

Summary

This study tests new treatments for endometrial cancer based on the genetic makeup of each person's tumor. About 1,615 participants will be assigned to one of four trials depending on their cancer's molecular profile. The goal is to see if these tailored therapies can prevent the cancer from coming back.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amphia Ziekenhuis

    RECRUITING

    Breda, Netherlands

    Contact Email: •••••@•••••

  • Amsterdam University Medical Center

    RECRUITING

    Amsterdam, Netherlands

    Contact

    Contact Email: •••••@•••••

  • Catharina Ziekenhuis

    RECRUITING

    Eindhoven, Netherlands

    Contact Email: •••••@•••••

  • Erasmus Medical Center

    RECRUITING

    Rotterdam, Netherlands

    Contact Email: •••••@•••••

  • Haags Medisch Centrum

    RECRUITING

    The Hague, Netherlands

    Contact Email: •••••@•••••

  • Instituut Verbeeten

    RECRUITING

    Breda, Netherlands

    Contact Email: •••••@•••••

  • Medisch Spectrum Twente

    RECRUITING

    Enschede, Netherlands

    Contact Email: •••••@•••••

  • The MMRd-GREEN trial: Leiden University Medical Center

    RECRUITING

    Leiden, 2333ZA, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The NSMP-ORANGE trial: Barts Health NHS Trust

    NOT_YET_RECRUITING

    London, United Kingdom

    Contact Email: •••••@•••••

  • The NSMP-ORANGE trial: Manchester Academic Health Science Centre, St Mary's Hospita

    NOT_YET_RECRUITING

    Manchester, United Kingdom

    Contact Email: •••••@•••••

  • The POLEmut-BLUE trial: Princess Margaret Cancer Centre, University of Toronto

    RECRUITING

    Toronto, Canada

    Contact Email: •••••@•••••

  • The POLEmut-BLUE trial: University of British Columbia

    RECRUITING

    Vancouver, Canada

    Contact Email: •••••@•••••

  • The p53abn-RED trial: Institute Gustave Roussy

    NOT_YET_RECRUITING

    Villejuif, France

    Contact Email: •••••@•••••

  • Universitair Medisch Centrum Groningen

    RECRUITING

    Groningen, Netherlands

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.