Heart bypass graft drug combo trial pulled before it began
NCT ID NCT06730945
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study planned to test whether taking two blood vessel-relaxing drugs (isosorbide mononitrate and amlodipine) for 24 weeks after coronary bypass surgery could prevent failure of the radial artery graft. The trial was withdrawn before enrolling any participants, so no data were collected. The intended participants were adults who had just received a radial artery graft during bypass surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
isosorbide mononitrate and amlodipine
What this could lead to
If it had worked, this could point toward a simple oral treatment to keep radial artery grafts open longer after bypass surgery.
What could go wrong
The trial was withdrawn before any participants enrolled, so no results are available. Even if conducted, the treatment might not reduce graft failure and could cause low blood pressure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ruijin Hospital Shanghai Jiao Tong University School of Medicine
Shanghai, China