New hydrogel aims to speed recovery after brain surgery

NCT ID NCT05898074

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a special hydrogel (PuraGel) placed inside the nose after skull base surgery to see if it helps the surgical site heal faster and reduces pain. Thirty adults having this surgery will be randomly assigned to get either the hydrogel or a standard silicone splint. Doctors will check healing and pain levels at 1, 4, and 12 weeks after surgery.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
PuraGel (RADA16) Hydrogel
What this could lead to
If it works, this could lead to faster healing and less pain after skull base surgery.
What could go wrong
This is a small early study with only 30 people, so results may not apply to everyone. The hydrogel is a device, not a drug, so benefits may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Indiana University

    RECRUITING

    Indianapolis, Indiana, 46202, United States

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Other studies related to the condition(s) this trial covers.