Can a glue stop spinal fluid leaks after surgery?
NCT ID NCT07754344
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This trial tests whether a special medical adhesive can create a watertight seal over the spinal lining after surgery, preventing cerebrospinal fluid leaks. About 141 adults undergoing spinal surgery with confirmed fluid leakage will be randomly assigned to receive either the adhesive or standard reinforcement. The main goal is to see if the adhesive successfully stops the leak during surgery, with follow-up checks for leaks and side effects over 90 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A medical adhesive applied over the sutured spinal lining to create a watertight seal and prevent cerebrospinal fluid leakage.
- What this could lead to
- If effective, this adhesive could reduce the risk of cerebrospinal fluid leaks after spinal surgery, potentially shortening hospital stays and improving recovery.
- What could go wrong
- The trial is still in Phase 3 and results are not yet known. The adhesive may not seal as well as standard methods, and there could be risks like allergic reactions or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Nanfang Hospital, Southern Medical University
Guangzhou, China
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Peking University Third Hospital
Beijing, China
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Shenzhen Second People's Hospital
Shenzhen, China
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The First Affiliated Hospital of Nanchang University
Nanchang, China
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Xi'an Honghui Hospital
Xi'an, China
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Xuanwu Hospital, Capital Medical University
Beijing, China
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