Could a natural compound in apples prevent cancer in rare disease patients?

NCT ID NCT03476330

First seen Apr 21, 2026 · Last updated May 14, 2026 · Updated 4 times

Summary

This study tested whether quercetin, a natural compound found in fruits and vegetables, can prevent or delay squamous cell carcinoma (a type of mouth cancer) in people with Fanconi anemia, a rare genetic disorder that raises cancer risk. 48 participants took quercetin pills, and researchers measured changes in cheek cells to see if cancer-related damage was reduced. The goal was to find a safer way to lower cancer risk without harsh treatments like chemotherapy or radiation.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

Conditions

Explore the condition pages connected to this study.