Schizophrenia treatment could go from daily pills to four shots a year
NCT ID NCT06276361
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-phase study tested a new long-acting injection of the antipsychotic drug risperidone that would only need to be given once every three months. Fifty-eight adults with stable schizophrenia received a single shot at different doses to measure how the drug moves through the body and to check for safety issues. The goal is to see if this quarterly shot could eventually offer a more convenient option for people who currently take daily risperidone pills.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
risperidone (quarterly injection)
What this could lead to
If successful, this could lead to a once-every-three-months injection for schizophrenia, reducing the need for daily pills.
What could go wrong
This is a very early Phase 1 study with only 58 participants, focused on safety and drug levels, not on how well it controls symptoms. The injection may not work as well as daily medication, and side effects are still being evaluated.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Investigational Site
Amman, Jordan