New study probes stomach valve problems in gastroparesis patients

NCT ID NCT04661215

Recruiting now Knowledge-focused Sponsor: Johns Hopkins Bloomberg School of Public Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find out if people with gastroparesis (stomach paralysis) have abnormalities in the pyloric sphincter, the valve between the stomach and small intestine. Researchers will use special imaging tools to measure how flexible and open this valve is. The study will enroll 150 adults with gastroparesis symptoms to better understand how common these valve problems are.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand the role of the pyloric sphincter in gastroparesis, potentially leading to improved diagnosis or targeted treatments.
What could go wrong: This is an observational study, not a treatment trial. It will not directly benefit participants and may not find clear abnormalities. Results may not apply to all patients with gastroparesis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastroparesis idiopathic gastroparesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC GASTROPARESIS GASTROPARESIS IDIOPATHIC GASTRIC MOTILITY DISORDER

Contacts and locations

Locations

Massachusetts General
RECRUITING

Boston, Massachusetts, 02114, United States
Mayo Clinic Arizona
RECRUITING

Scottsdale, Arizona, 85259, United States
Temple University
RECRUITING

Philadelphia, Pennsylvania, 19140, United States
University of Louisville
RECRUITING

Louisville, Kentucky, 40202, United States
Wake Forest University Health Sciences
RECRUITING

Winston-Salem, North Carolina, 27157, United States

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