Eye test could spot kids at risk for opioid breathing trouble

NCT ID NCT07573150

Recruiting now Knowledge-focused Sponsor: NeurOptics Inc Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a device that measures pupil reactions can help identify children at risk for opioid-induced respiratory depression after tonsillectomy. About 300 children will have their pupils measured before, during, and after surgery. The goal is to see if pupil patterns relate to breathing problems, which could lead to better monitoring in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple, non-invasive way to predict which children are at risk for dangerous breathing problems after surgery and opioids.
What could go wrong: This is an early observational study, not a treatment trial. The pupil measurements are not used to guide care, so it may not prove that using them actually prevents harm.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute opioid poisoning agnosia Hypoventilation Postoperative Complications respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID INDUCED RESPIRATORY DEPRESSION POSTOPERATIVE COMPLICATIONS (CARDIOPULMONARY) RESPIRATORY COMPLICATIONS DUE TO ANESTHESIA

Contacts and locations

Locations

UCSF Benioff Children's Hospital
NOT_YET_RECRUITING

San Francisco, California, 94158, United States
UPMC Children's Hospital of Pittsburgh
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States

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