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New study aims to pinpoint hidden cause of chronic constipation

NCT ID NCT07683390

Knowledge-focused Sponsor: Third Military Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study looks at people with chronic constipation to see if a specific muscle problem called puborectalis syndrome can be better identified using three different tests: defecography, high-resolution anorectal manometry, and pelvic floor ultrasound. Researchers will compare results between those with and without this condition to find the most accurate way to diagnose it. The goal is to improve diagnosis and treatment for people whose constipation is caused by this muscle issue.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to more accurate diagnosis of a specific type of constipation, helping doctors choose better treatments.
What could go wrong
This is an observational study, not a treatment trial. It may not change clinical practice if results are not clear or generalizable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

164 people

The number who actually took part.

Started

Jul 2023

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patients with suspected PRS-related DD

Ages

16 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ranges from 16 to 85 years old. 2. Constipation patients should meet the Rome Ⅳ criteria for chronic constipation (must include two or more of the following: ① At least 25% of bowel movements are strenuous; ② At least 25% of bowel movements are lumpy or hard stools; ③ At least 25% of bowel movements are accompanied by a sense of incomplete evacuation; ④ At least 25% of bowel movements are associated with a feeling of anorectal obstruction or blockage; ⑤ At least 25% of bowel movements require manual assistance; ⑥ Fewer than 3 bowel movements per week). The healthy volunteer group has no above - mentioned constipation symptoms. 3. Participants should be able to understand and complete relevant questionnaires. 4. Participants should be willing to follow the research protocol and sign the informed consent form. Exclusion Criteria: 1. Pregnant women and lactating women 2. Suffering from gastrointestinal and other malignant tumors 3. Suffering from diseases such as diabetes and Parkinson's disease 4. Currently participating in other clinical trials

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Conditions

The condition(s) this trial relates to.

anismus constipation disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dyssynergic defecation Impaired rectal evacuation Puborectalis syndrome

Contacts and locations

Locations

  • Army Medical Center (Daping Hospital)

    Yuzhong, Chongqing Municipality, 400042, China

More trials for these conditions

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