Gut bacteria boost: probiotic shows promise for constipation relief
NCT ID NCT07649564
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a daily probiotic called Weizmannia coagulans BC99 can improve symptoms of chronic constipation in adults. One hundred participants took either the probiotic or a placebo for a period, and researchers measured changes in stool consistency and gut bacteria. The goal was to see if the probiotic could ease constipation without the need for laxatives.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Weizmannia coagulans BC99 probiotic
What this could lead to
If it works, this could offer a natural, over-the-counter option to help relieve chronic constipation without harsh laxatives.
What could go wrong
This is a small, completed trial with only 100 participants, so results may not apply to everyone. The effect may be modest and not a cure for underlying causes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The School of Food and Bioengineering, Henan University of Science and Technolog
Luoyang, Henan, 471000, China