Gut bacteria boost: probiotic shows promise for constipation relief

NCT ID NCT07649564

Completed Symptom relief Sponsor: Wecare Probiotics Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a daily probiotic called Weizmannia coagulans BC99 can improve symptoms of chronic constipation in adults. One hundred participants took either the probiotic or a placebo for a period, and researchers measured changes in stool consistency and gut bacteria. The goal was to see if the probiotic could ease constipation without the need for laxatives.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Weizmannia coagulans BC99 probiotic
What this could lead to: If it works, this could offer a natural, over-the-counter option to help relieve chronic constipation without harsh laxatives.
What could go wrong: This is a small, completed trial with only 100 participants, so results may not apply to everyone. The effect may be modest and not a cure for underlying causes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

constipation disorder neurodegeneration, childhood-onset, stress-induced, with variable ataxia and seizures neuroendocrine cell hyperplasia of infancy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CON CON S TI CONS TI

Contacts and locations

Locations

The School of Food and Bioengineering, Henan University of Science and Technolog

Luoyang, Henan, 471000, China

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