Magic mushroom microdoses could soothe End-of-Life anxiety

NCT ID NCT07063862

First seen Feb 01, 2026 · Last updated May 13, 2026 · Updated 10 times

Summary

This study tests whether very small, non-hallucinogenic doses of psilocybin (the active ingredient in 'magic mushrooms') can reduce depression, anxiety, and loss of purpose in 120 adults with advanced illness who are under palliative care. Participants take either psilocybin or a placebo daily for 2 weeks, and researchers compare changes in distress. The goal is to find a safe, quick, and accessible treatment for psychological suffering near the end of life.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bruyere Health

    RECRUITING

    Ottawa, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • McGill University Health Centre

    NOT_YET_RECRUITING

    Montreal, Quebec, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Providence Care Hospital

    RECRUITING

    Kingston, Ontario, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • South Lake Regional Health Centre

    RECRUITING

    Newmarket, Ontario, Canada

    Contact Phone: •••-•••-••••

  • St. Joseph's Healthcare

    NOT_YET_RECRUITING

    London, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Ottawa Hospital

    NOT_YET_RECRUITING

    Ottawa, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • William Osler Health System

    NOT_YET_RECRUITING

    Brampton, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.