Magic mushroom compound tested for Post-Surgery pain and opioid addiction

NCT ID NCT07406828

First seen Feb 17, 2026 · Last updated May 09, 2026 · Updated 8 times

Summary

This early-stage trial will test whether a single dose of psilocybin (the active ingredient in magic mushrooms) is safe and practical for adults with opioid use disorder who are recovering from trauma surgery. Seventy participants will receive the drug during their hospital stay and be monitored for pain, mood, and opioid use. The main goals are to see if this approach is feasible and safe, with a focus on reducing pain and improving emotional recovery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • UPMC Presbyterian

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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