Your favorite songs may boost Psilocybin's Mind-Altering effects, study suggests

NCT ID NCT07180108

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether listening to personally meaningful music during a psilocybin session changes emotions, brain activity, and well-being more than standard playlists. One hundred healthy adults will take a single 25 mg dose of psilocybin and listen to one of five music conditions. Researchers will measure brain waves, heart rate, and mood through questionnaires and scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: psilocybin (25 mg pill)
What this could lead to: If successful, this could reveal how to design music playlists that enhance the positive effects of psilocybin for future therapeutic use.
What could go wrong: This is an early Phase 1 study in healthy volunteers, not patients. It focuses on brain and emotional responses, not treating any disease. Results may not apply to clinical settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MUSIC INTERVENTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MUSIC INTERVENTION PSILOCYBIN

Contacts and locations

Locations

Center for Psychedelics and Consciousness Research in the Behavioral Biology Research Center

Baltimore, Maryland, 21224, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.