Can a risk score and MRI outsmart dense breasts?
NCT ID NCT07277738
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding an MRI to the yearly mammogram can help find breast cancer earlier in women with dense breasts. Participants will have a mammogram and a risk score calculated from it. Those with a high risk score will be offered an MRI. The goal is to see if this approach reduces cancers found between screenings or at a later stage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Prognosia Breast (a mammogram-based risk algorithm) and MRI
What this could lead to
If successful, this could show that using a risk score to select women for supplemental MRI reduces late-stage or interval breast cancers.
What could go wrong
This is a small, early feasibility study (78 participants) and not yet recruiting. The risk score may not accurately predict who benefits from MRI, and MRI can lead to false alarms or unnecessary biopsies.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Contact
Contact
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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