Cure My Disease

Don't miss your cure!

 Log in / Sign up

Nanoengineered patches and injectables aim to fight cancer locally

NCT ID NCT05893888

Recruiting now Disease control Sponsor: Privo Technologies Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests three new ways to deliver the chemotherapy drug cisplatin directly to tumors in the mouth or lungs. The goal is to kill cancer cells while reducing side effects on the rest of the body. About 40 adults with early-stage oral or lung cancer will receive the treatment as a patch, a surgical implant, or an injection. The trial is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cisplatin (delivered via PRV111 patch, PRV211 intraoperative system, or PRV131 injectable)
What this could lead to
If successful, this could offer a more targeted, less toxic way to deliver chemotherapy directly to tumors, potentially improving outcomes for oral and lung cancers.
What could go wrong
This is an early-phase trial with only 40 participants, so results may not apply broadly. The treatments involve cisplatin, which can cause side effects like kidney damage and nerve issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CARCINOMA IN SITU OF THE LIP OR ORAL CAVITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

lip and oral cavity squamous cell carcinoma lung cancer oral cavity carcinoma in situ oral cavity squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORAL SQUAMOUS CELL CARCINOMA

Contacts and locations

Locations

  • City of Hope National Medical Center

    RECRUITING

    Duarte, California, 91010, United States

  • Miami Cancer Institute

    RECRUITING

    Miami, Florida, 33176, United States

  • The Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • The University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.