Can a blood injection strengthen pelvic tissue after prolapse repair?
NCT ID NCT07150442
First seen Jun 25, 2026 · Last updated Jul 29, 2026 · Updated 3 times
Summary
This study tests whether injecting platelet-rich plasma (PRP) into the vaginal tissue during pelvic organ prolapse surgery improves healing. Thirty postmenopausal women with moderate-to-severe prolapse will receive either PRP or a placebo injection during surgery. Researchers will measure collagen ratios and other tissue markers before and 8 weeks after surgery to see if PRP helps strengthen the pelvic floor.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Platelet-rich plasma (PRP) injection
- What this could lead to
- If it works, this could show that adding PRP to prolapse surgery improves tissue strength and reduces the chance of prolapse returning.
- What could go wrong
- This is a very small, early study (30 people) looking at tissue markers, not long-term outcomes. PRP may not provide any benefit over surgery alone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Biomedical Science Doctoral Programme Faculty of Medicine Andalas University/ Urogynecology Division Obstetrics and Gynecology Department M Djamil Hospital Padang
Padang, West Sumatera, Indonesia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Blood-Derived injection strengthen pelvic floor repair?
- Large study to track bladder leaks after prolapse surgery in over 1,000 women
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