Blood-Based injection may ease jaw locking and pain

NCT ID NCT07532798

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether platelet-rich plasma (PRP) injections can help people with a jaw condition where the joint slips out of place (TMJ subluxation). Forty adults received two injections of PRP, made from their own blood, with either a low or high platelet concentration. Researchers measured pain, locking episodes, mouth opening, and joint clicking before treatment and again after 6 months and 5 years to see if the platelet level affects results.

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Conditions

The condition(s) this trial relates to.

temporomandibular joint disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University

    Cairo, Egypt