Can primary care clinics help curb the opioid crisis? a major trial tests a Team-Based model

NCT ID NCT03407638

Completed Disease control Sponsor: Kaiser Permanente Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether a team-based approach, including a dedicated nurse care manager, can help primary care clinics provide medication treatment for opioid use disorder. The study involves 12 clinics across five U.S. states, with half using the new approach and half continuing usual care. Researchers will measure whether more patients receive and stay on treatment, and whether this reduces emergency room visits and hospital stays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: buprenorphine or injectable naltrexone
What this could lead to: If successful, this could show that a team-based primary care model is an effective way to expand access to opioid use disorder treatment, potentially reducing overdoses and hospital visits.
What could go wrong: This is an implementation trial, not a test of the medications themselves. Results may vary across different health systems, and the intervention may not be adopted widely if it proves too costly or complex.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID-USE DISORDER

Contacts and locations

Locations

Harris Health System

Houston, Texas, 77054, United States
Henry Ford Health System

Detroit, Michigan, 48202, United States
Kaiser Permanente Washington

Seattle, Washington, 98112, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
MultiCare Health System

Tacoma, Washington, 98405, United States
University of Miami Health System

Miami, Florida, 33136, United States

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