Can primary care clinics help curb the opioid crisis? a major trial tests a Team-Based model

NCT ID NCT03407638

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether a team-based approach, including a dedicated nurse care manager, can help primary care clinics provide medication treatment for opioid use disorder. The study involves 12 clinics across five U.S. states, with half using the new approach and half continuing usual care. Researchers will measure whether more patients receive and stay on treatment, and whether this reduces emergency room visits and hospital stays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

buprenorphine or injectable naltrexone

What this could lead to

If successful, this could show that a team-based primary care model is an effective way to expand access to opioid use disorder treatment, potentially reducing overdoses and hospital visits.

What could go wrong

This is an implementation trial, not a test of the medications themselves. Results may vary across different health systems, and the intervention may not be adopted widely if it proves too costly or complex.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Harris Health System

    Houston, Texas, 77054, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Kaiser Permanente Washington

    Seattle, Washington, 98112, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • MultiCare Health System

    Tacoma, Washington, 98405, United States

  • University of Miami Health System

    Miami, Florida, 33136, United States