Brain cancer radiation showdown: which therapy saves your smarts?

NCT ID NCT03180502

First seen May 21, 2026 · Last updated May 25, 2026 · Updated 1 time

Summary

This study compares proton beam therapy to standard photon radiation (IMRT) in 120 people with IDH-mutant grade II or III gliomas. The goal is to see which method better preserves memory and thinking skills after treatment. Both techniques aim to deliver radiation precisely to the tumor while minimizing harm to healthy brain tissue.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GLIOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Boca Raton Regional Hospital

    Boca Raton, Florida, 33486, United States

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Central Maryland Radiation Oncology in Howard County

    Columbia, Maryland, 21044, United States

  • Emory Proton Therapy Center

    Atlanta, Georgia, 30308, United States

  • Emory University Hospital Midtown

    Atlanta, Georgia, 30308, United States

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • FHCC at Northwest Hospital

    Seattle, Washington, 98133, United States

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York, New York, 10016, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • MaineHealth Maine Medical Center- Scarborough

    Scarborough, Maine, 04074, United States

  • Maryland Proton Treatment Center

    Baltimore, Maryland, 21201, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

  • Mercy Hospital Springfield

    Springfield, Missouri, 65804, United States

  • Miami Cancer Institute

    Miami, Florida, 33176, United States

  • Northwestern Medicine Cancer Center Delnor

    Geneva, Illinois, 60134, United States

  • Northwestern Medicine Cancer Center Warrenville

    Warrenville, Illinois, 60555, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • UM Baltimore Washington Medical Center/Tate Cancer Center

    Glen Burnie, Maryland, 21061, United States

  • UM Upper Chesapeake Medical Center

    Bel Air, Maryland, 21014, United States

  • University Hospitals Parma Medical Center

    Parma, Ohio, 44129, United States

  • University Hospitals Portage Medical Center

    Ravenna, Ohio, 44266, United States

  • University of Alabama at Birmingham Cancer Center

    Birmingham, Alabama, 35233, United States

  • University of Kansas Cancer Center

    Kansas City, Kansas, 66160, United States

  • University of Kansas Cancer Center - Lee's Summit

    Lee's Summit, Missouri, 64064, United States

  • University of Kansas Cancer Center - North

    Kansas City, Missouri, 64154, United States

  • University of Kansas Cancer Center at North Kansas City Hospital

    North Kansas City, Missouri, 64116, United States

  • University of Kansas Cancer Center-Overland Park

    Overland Park, Kansas, 66210, United States

  • University of Kansas Hospital-Westwood Cancer Center

    Westwood, Kansas, 66205, United States

  • University of Maryland/Greenebaum Cancer Center

    Baltimore, Maryland, 21201, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Pennsylvania/Abramson Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

  • University of Washington Medical Center - Montlake

    Seattle, Washington, 98195, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.