Protein and exercise combo tested to fight muscle loss in sick kids

NCT ID NCT05296096

Completed Disease control Sponsor: Boston Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether giving critically ill children on breathing machines extra protein along with a personalized exercise program could help preserve muscle mass and improve recovery. The trial enrolled 18 children in the ICU and measured how feasible and safe the approach was. The goal is to use these results to design a larger study that could lead to better outcomes for young patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: high protein diet and individualized exercise program
What this could lead to: If this approach works, it could help prevent muscle loss and improve recovery in children who are critically ill and on breathing machines.
What could go wrong: This is a very small pilot study with only 18 participants, so results may not apply to all children. The high protein diet may cause kidney strain or digestive issues.

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Conditions

The condition(s) this trial relates to.

childhood acute lymphoblastic leukemia Motor Activity muscular atrophy Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MOBILITY MUSCLE LOSS PEDIATRIC ALL PROTEIN

Contacts and locations

Locations

Boston Children's Hospital

Boston, Massachusetts, 02115, United States
Johns Hopkins Hospital

Baltimore, Maryland, 21218, United States

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