New drug combo tested for Tough-to-Treat prostate cancer
NCT ID NCT04019327
Summary
This study tested a combination of two drugs, talazoparib and temozolomide, for men with advanced prostate cancer that had spread and stopped responding to standard hormone therapies. The first part of the study aimed to find the safest dose, and the second part tested how well that dose worked at controlling the cancer. It involved 16 participants who did not have specific genetic mutations that make other similar drugs effective.
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Contacts and locations
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Locations
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Lehigh Valley Health Network (Data Collection Only)
Allentown, Pennsylvania, 18103, United States
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack (Limited protocol activity)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, 10604, United States
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University of Virginia
Charlottesville, Virginia, 22908, United States
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University of Wisconsin
Madison, Wisconsin, 53792, United States
Conditions
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