Eye treatment may lift mood: PROSE lenses tested for depression relief

NCT ID NCT07195721

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether PROSE treatment—a custom contact lens that soothes the eye surface—can also improve mental health in people with major depression. Researchers will track depression scores and eye symptoms in 200 adults over time. The goal is to see if treating severe dry eye can lift mood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PROSE treatment (a special contact lens that protects the eye surface)

What this could lead to

If it works, this could show that treating severe dry eye with PROSE lenses also eases depression symptoms.

What could go wrong

This is an early-stage trial with no control group, so results may not prove cause and effect. The effect on mood might be small or not last.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BostonSight

    RECRUITING

    Needham, Massachusetts, 02494, United States

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••