Heart drug may worsen advanced liver disease – major trial underway

NCT ID NCT07652203

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether propranolol, a drug often used for high blood pressure, helps or harms people with advanced cirrhosis (severe liver scarring). The trial will include 466 adults with a MELD score over 9, meaning their liver disease is fairly advanced. Researchers will compare those who take propranolol to those who do not, tracking how long it takes for liver complications to get worse.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Gastroenterology, General Hospital of Northern Theater Command (formerly called General Hospital of Shenyang Military Area)

    Shenyang, Liaoning, China

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Other studies related to the condition(s) this trial covers.