New study seeks early warning signs for pregnancy complications in lupus patients

NCT ID NCT00198068

First seen Apr 29, 2026 · Last updated Jun 19, 2026 · Updated 8 times

Summary

This observational study is following 700 pregnant women with lupus or antiphospholipid syndrome across nine medical centers. Researchers are looking at specific proteins in the blood to see if they can predict serious pregnancy complications like fetal death, preterm delivery, or low birth weight. The goal is to find early markers that could help doctors manage these high-risk pregnancies better.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Medical Center

    COMPLETED

    New York, New York, 10032, United States

  • Guy's & St Thomas' NHS Foundation Trust

    COMPLETED

    London, SE1 7EH, United Kingdom

  • Hospital for Special Surgery

    RECRUITING

    New York, New York, 10021, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Johns Hopkins Hospital

    COMPLETED

    Baltimore, Maryland, 21287, United States

  • Mt. Sinai Hospital

    RECRUITING

    Toronto, Ontario, M5G 2K4, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Langone Medical Center/Hospital for Joint Diseases

    RECRUITING

    New York, New York, 10016, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern University

    COMPLETED

    Chicago, Illinois, 60611, United States

  • Oklahoma Medical Research Foundation

    COMPLETED

    Oklahoma City, Oklahoma, 73104, United States

  • University of Chicago

    COMPLETED

    Chicago, Illinois, 60637, United States

  • University of Utah Salt Lake City

    RECRUITING

    Salt Lake City, Utah, 84132, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors identify high-risk pregnancies early and improve monitoring for women with lupus or antiphospholipid syndrome.

What could go wrong

This is an observational study, not a treatment trial. It may not lead to direct changes in care, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

antiphospholipid syndrome systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.