Could a 14-Hour nightly fast ward off blood cancer?
NCT ID NCT05565638
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 33 times
Summary
This study tested whether fasting for 14 hours each night helps overweight people with early blood conditions (MGUS or smoldering myeloma) lose weight and lower their risk of developing multiple myeloma. Twenty-three participants were randomly assigned to either the fasting program or a healthy lifestyle education group for 4 months. The goal was to see if this simple dietary change could improve body composition and reduce cancer-related proteins in the blood.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
prolonged nightly fasting (behavioral intervention)
What this could lead to
If it works, this could point toward a simple lifestyle change to reduce the risk of blood cancer in people with early warning signs.
What could go wrong
This is a very small, early study with only 23 participants, so results may not apply to everyone. Fasting for 14 hours nightly may be hard to stick with long-term.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.