Gut-Brain hope: probiotic trial targets depression

NCT ID NCT07667530

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking a probiotic supplement called Ecologic® Barrier for 16 weeks can reduce depressive symptoms and change brain activity in adults aged 25-40 with mild-to-moderate depression. Participants will be randomly assigned to receive the probiotic or a placebo. The goal is to see if this supplement offers a safe, non-drug way to ease depression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Probiotic supplement (Ecologic® Barrier)

What this could lead to

If it works, this could point toward a simple, non-drug option to help manage mild-to-moderate depression.

What could go wrong

This is an early-stage study with only 76 people, so results may not apply widely. The supplement may have no effect on mood or brain activity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EXECUTIVE FUNCTION (COGNITION) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • School of Psychology and Clinical Languages

    London, RG6 6UR, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact