Could probiotics soothe chemo belly? new trial hopes so

NCT ID NCT07605728

Recruiting now Symptom relief Sponsor: Leeuwenhoek Laboratories Co. Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a probiotic supplement can help reduce diarrhea and belly discomfort in breast cancer patients taking the drug Abemaciclib. About 80 participants will get either the supplement or a placebo for two months, while also using standard anti-diarrhea medicine. Researchers will track symptom severity and check blood for metabolic changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Synbiotic supplement (Bifidobacterium longum, Oligonol® lychee polyphenol, and postbiotics)
What this could lead to: If it works, this could offer a simple, natural way to reduce gut side effects from a common breast cancer drug, improving quality of life during treatment.
What could go wrong: This is a small, early-phase study (80 people) testing a dietary supplement, not a drug. The effect may be modest or no better than placebo, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm chemotherapy-induced toxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER CHEMOTHERAPY-INDUCED DIARRHEA

Contacts and locations

Locations

National Taiwan University Hospital
RECRUITING

Taipei, Taiwan

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